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KMID : 0383820090670060560
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Tuberculosis and Respiratory Diseases
2009 Volume.67 No. 6 p.560 ~ p.564
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A Case of Sarcoidosis with Pancytopenia as Resulting from Bone Marrow Involvement
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Park Tai-Sun
Kim Dae-Young
Park Seo-Jin
Kim Yi-Rang
Na Soo-Young
Park Jin-Wook
Oh Dong-Wook
Choi Jun-Seok
Jo Jung-Min
Chang You-Jin
Kim Wong-Young
Choi Chang-Min
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Abstract
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Sarcoidosis is a granulomatous disease that can involve any organ, although it primarily involves the lungs, intrathoracic lymph nodes, skin, and eyes. We present a case of sarcoidosis with pancytopenia, resulting from bone marrow involvement. A 35-year-old man was admitted to hospital for chronic cough and blurred vision. On chest computed tomography, there were multiple pulmonary nodules and mediastinal lymph nodes enlargement. As the patient also showed pancytopenia, we performed a bone marrow biopsy, as well as a transbronchial lung biopsy. Both biopsies showed non-caseating granulomas. We diagnosed the patient with sarcoidosis with pulmonary, bone marrow, uvea, liver and spleen involvement. After oral steroid therapy, the patient’s symptoms as well as his pancytopenia improved. We present this case to demonstrate the significance of bone marrow biopsy in cases of sarcoidosis with pancytopenia, as well the possibility of clinical improvement with steroid treatment.
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KEYWORD
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Sarcoidosis, Pancytopenia, Bone Marrow
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